Log in to save to my catalogue

Decoding mRNA translatability and stability from the 5′ UTR

Decoding mRNA translatability and stability from the 5′ UTR

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2428062132

Decoding mRNA translatability and stability from the 5′ UTR

About this item

Full title

Decoding mRNA translatability and stability from the 5′ UTR

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2020-09, Vol.27 (9), p.814-821

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Precise control of protein synthesis by engineering sequence elements in 5′ untranslated regions (5′ UTRs) remains a fundamental challenge. To accelerate our understanding of the
cis
-regulatory code embedded in 5′ UTRs, we devised massively parallel reporter assays from a synthetic messenger RNA library composed of over one million 5′ UTR va...

Alternative Titles

Full title

Decoding mRNA translatability and stability from the 5′ UTR

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2428062132

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2428062132

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/s41594-020-0465-x

How to access this item