Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
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Author / Creator
Wouters, Jasper , Kalender-Atak, Zeynep , Minnoye, Liesbeth , Spanier, Katina I. , De Waegeneer, Maxime , Bravo González-Blas, Carmen , Mauduit, David , Davie, Kristofer , Hulselmans, Gert , Najem, Ahmad , Dewaele, Michael , Pedri, Dennis , Rambow, Florian , Makhzami, Samira , Christiaens, Valerie , Ceyssens, Frederik , Ghanem, Ghanem , Marine, Jean-Christophe , Poovathingal, Suresh and Aerts, Stein
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Melanoma cells can switch between a melanocytic and a mesenchymal-like state. Scattered evidence indicates that additional intermediate state(s) may exist. Here, to search for such states and decipher their underlying gene regulatory network (GRN), we studied 10 melanoma cultures using single-cell RNA sequencing (RNA-seq) as well as 26 additional c...
Alternative Titles
Full title
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
Authors, Artists and Contributors
Author / Creator
Kalender-Atak, Zeynep
Minnoye, Liesbeth
Spanier, Katina I.
De Waegeneer, Maxime
Bravo González-Blas, Carmen
Mauduit, David
Davie, Kristofer
Hulselmans, Gert
Najem, Ahmad
Dewaele, Michael
Pedri, Dennis
Rambow, Florian
Makhzami, Samira
Christiaens, Valerie
Ceyssens, Frederik
Ghanem, Ghanem
Marine, Jean-Christophe
Poovathingal, Suresh
Aerts, Stein
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2430656772
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2430656772
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-0547-3
