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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK...

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2431952125

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

About this item

Full title

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Publisher

Korea (South): Taylor & Francis

Journal title

Animal Cells and Systems, 2018, 22(5), , pp.273-280

Language

English

Formats

Publication information

Publisher

Korea (South): Taylor & Francis

More information

Scope and Contents

Contents

Leucine-rich repeat kinase 2 (LRRK2) is involved in Parkinson's disease (PD) pathology. A previous study showed that rotenone treatment induced apoptosis, mitochondrial damage, and nucleolar disruption via up-regulated LRRK2 kinase activity, and these effects were rescued by an LRRK2 kinase inhibitor. Heat-shock protein 70 (Hsp70) is an anti-oxidat...

Alternative Titles

Full title

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2431952125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2431952125

Other Identifiers

ISSN

1976-8354,2151-2485

E-ISSN

2151-2485

DOI

10.1080/19768354.2018.1518262

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