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ArticlesPeer ReviewedFull Text
Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia
Author / Creator:Kim, Beomsue ; Yang, Myung-Soon ; Choi, Dongjoo ; Kim, Jong-Hyeon ; Kim, Hye-Sun ; Seol, Wongi ; Choi, Sangdun ; Jou, Ilo ; Kim, Eun-Young ; Joe, Eun-hye
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e34693
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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss
Author / Creator:Ho, Dong-Hwan ; Nam, Daleum ; Seo, Mikyoung ; Park, Sung-Woo ; Seol, Wongi ; Son, Ilhong
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-03, Vol.11 (5), p.861
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Bi-directional regulation of AIMP2 and its splice variant on PARP-1-dependent neuronal cell death; Therapeutic implication for Parkinson's disease
Author / Creator:Lee, Min Hak ; Um, Ki-Hwan ; Lee, Seok Won ; Sun, Ye Ji ; Gu, Da-Hye ; Jo, Young Ok ; Kim, Sung Hyun ; Seol, Wongi ; Hwang, Hyorin ; Baek, Kyunghwa ; Choi, Jin Woo
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2024-01, Vol.12 (1), p.5-17, Article 5
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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity
Author / Creator:Seo, Hyemyung ; Son, Ilhong ; Joe, Eun-hye ; Jang, Jihoon ; Ho, Dong Hwan ; Seol, Wongi
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2016-01, Vol.2016 (2016), p.1-8
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G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses
Author / Creator:Ho, Dong Hwan ; Lee, Heajin ; Son, Ilhong ; Seol, Wongi
Publisher:England: Taylor & Francis
Journal title:Animal Cells and Systems, 2019, 23(2), , pp.106-111
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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease
Author / Creator:Ho, Dong Hwan ; Seo, Hyemyung ; Seol, Wongi ; Lee, Sung Ik ; Jeong, Soyeon ; Jang, Jihoon ; Son, Ilhong
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Parkinson's disease, 2018-01, Vol.2018 (2018), p.1-9
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Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease
Author / Creator:Nam, Daleum ; Kim, Ami ; Han, Sun Jung ; Lee, Sung-Ik ; Park, Sung-Hye ; Seol, Wongi ; Son, Ilhong ; Ho, Dong Hwan
Publisher:England: Taylor & Francis
Journal title:Animal Cells and Systems, 2021, 25(1), , pp.28-36
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Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1
Author / Creator:Han, Kyung A. ; Yoo, Lang ; Sung, Jee Y. ; Chung, Sun A. ; Um, Ji W. ; Kim, Hyeyoung ; Seol, Wongi ; Chung, Kwang C.
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in cellular neuroscience, 2017-05, Vol.11, p.125
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Androstane metabolites bind to and deactivate the nuclear receptor CAR-β
Author / Creator:Forman, Barry M. ; Tzameli, Iphigenia ; Choi, Hueng-Sik ; Chen, Jasmine ; Simha, Devendranath ; Seol, Wongi ; Evans, Ronald M. ; Moore, David D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1998-10, Vol.395 (6702), p.612-615
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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity
Author / Creator:Jang, Jihoon ; Oh, Hakjin ; Nam, Daleum ; Seol, Wongi ; Seo, Mi Kyoung ; Park, Sung Woo ; Kim, Hyung Gun ; Seo, Hyemyung ; Son, Ilhong ; Ho, Dong Hwan
Publisher:Korea (South): Taylor & Francis
Journal title:Animal Cells and Systems, 2018, 22(5), , pp.273-280
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Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression
Author / Creator:Ho, Dong Hwan ; Kim, Hyejung ; Kim, Jisun ; Sim, Hyuna ; Ahn, Hyunjun ; Kim, Janghwan ; Seo, Hyemyung ; Chung, Kwang Chul ; Park, Bum-Joon ; Son, Ilhong ; Seol, Wongi
Publisher:London: BioMed Central Ltd
Journal title:Molecular brain, 2017-10, Vol.10 (1), p.48-1, Article 48
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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors
Author / Creator:Park, Kyung-Soon ; Lee, Dong-ki ; Lee, Horim ; Lee, Yangsoon ; Jang, Young-Soon ; Kim, Yong Ha ; Yang, Hyo-Young ; Lee, Sung-Il ; Seol, Wongi ; Kim, Jin-Soo
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2003-10, Vol.21 (10), p.1208-1214
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Human zinc fingers as building blocks in the construction of artificial transcription factors
Author / Creator:Bae, Kwang-Hee ; Do Kwon, Young ; Shin, Hyun-Chul ; Hwang, Moon-Sun ; Ryu, Eun-Hyun ; Park, Kyung-Soon ; Yang, Hyo-Young ; Lee, Dong-ki ; Lee, Yangsoon ; Park, Jinwoo ; Sun Kwon, Heung ; Kim, Hyun-Won ; Yeh, Byung-Il ; Lee, Hyean-Woo ; Hyung Sohn, Soon ; Yoon, Joonho ; Seol, Wongi ; Kim, Jin-Soo
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2003-03, Vol.21 (3), p.275-280
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ArticlesPeer ReviewedFull Text
Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression
Author / Creator:Ho, Dong Hwan ; Kim, Hyejung ; Kim, Jisun ; Sim, Hyuna ; Ahn, Hyunjun ; Kim, Janghwan ; Seo, Hyemyung ; Chung, Kwang Chul ; Park, Bum-Joon ; Son, Ilhong ; Seol, Wongi
Publisher:London: BioMed Central Ltd
Journal title:Molecular brain, 2015-09, Vol.8 (1), Article 54
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ArticlesPeer ReviewedFull Text
Estrogen Receptor-α Mediates the Effects of Estradiol on Telomerase Activity in Human Mesenchymal Stem Cells
Author / Creator:Cha, Y. (Pochon CHA University, Seoul, Republic of Korea) ; Kwon, S.J. (Pochon CHA University, Seoul, Republic of Korea) ; Seol, W.G. (Inje University, Busan, Republic of Korea) ; Park, K.S. (Pochon CHA University, Seoul, Republic of Korea), E-mail: kspark@cha.ac.kr
Publisher:United States: 한국분자세포생물학회
Journal title:Molecules and Cells, 2008, 26(5), , pp.454-458
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ArticlesPeer ReviewedFull Text
Genetic Dissection of Protein-Protein Interactions in Multi-tRNA Synthetase Complex
Author / Creator:Rho, Seung Bae ; Kim, Min Jung ; Lee, Jong Sang ; Seol, Wongi ; Motegi, Hiromi ; Kim, Sunghoon ; Shiba, Kiyotaka
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4488-4493
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Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2
Author / Creator:Yun, Hye Jin ; Cho, Young-Hwa ; Moon, Youngsun ; Park, Young Woo ; Yoon, Hye-Kyoung ; Kim, Yeun-Ju ; Cho, Sung-Ha ; Lee, Young-Ill ; Kang, Bong-Su ; Kim, Wun-Jae ; Park, Keerang ; Seol, Wongi
Publisher:London: Nature Publishing Group UK
Journal title:Experimental & molecular medicine, 2008-06, Vol.40 (3), p.345-353
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Activation of the Orphan Receptor RIP14 by Retinoids
Author / Creator:Zavacki, Ann Marie ; Lehmann, Jurgen M. ; Seol, Wongi ; Willson, Timothy M. ; Kliewer, Steven A. ; Moore, David D.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1997-07, Vol.94 (15), p.7909-7914
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ArticlesPeer ReviewedFull Text
Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease
Author / Creator:Son, Ilhong ; Seo, Hyemyung ; Yi, Sanghak ; Ho, Dong Hwan ; Seol, Wongi
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2014-01, Vol.2014 (2014), p.1-8
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LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells
Author / Creator:Ho, Dong Hwan ; Nam, Daleum ; Seo, Mi Kyoung ; Park, Sung Woo ; Seol, Wongi ; Son, Ilhong
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.9969842
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Showing 1 to 20 of 37 results

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Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia

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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

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Bi-directional regulation of AIMP2 and its splice variant on PARP-1-dependent neuronal cell death; Therapeutic implication for Parkinson's disease

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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

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G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

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Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

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Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

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Androstane metabolites bind to and deactivate the nuclear receptor CAR-β

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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

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Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

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Human zinc fingers as building blocks in the construction of artificial transcription factors

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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

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Estrogen Receptor-α Mediates the Effects of Estradiol on Telomerase Activity in Human Mesenchymal Stem Cells

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Genetic Dissection of Protein-Protein Interactions in Multi-tRNA Synthetase Complex

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Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2

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Activation of the Orphan Receptor RIP14 by Retinoids

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Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

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LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells

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