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Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal st...

Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2448843009

Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells

About this item

Full title

Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2020-11, Vol.52 (11), p.1227-1238

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Adipocyte differentiation is driven by waves of transcriptional regulators that reprogram the enhancer landscape and change the wiring of the promoter interactome. Here, we use high-throughput chromosome conformation enhancer capture to interrogate the role of enhancer-to-enhancer interactions during differentiation of human mesenchymal stem cells....

Alternative Titles

Full title

Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2448843009

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2448843009

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-020-0709-z

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