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Active turnover of DNA methylation during cell fate decisions

Active turnover of DNA methylation during cell fate decisions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2449178269

Active turnover of DNA methylation during cell fate decisions

About this item

Full title

Active turnover of DNA methylation during cell fate decisions

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2021-01, Vol.22 (1), p.59-66

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

DNA methylation is a key layer of epigenetic regulation. The deposition of methylation marks relies on the catalytic activity of DNA methyltransferases (DNMTs), and their active removal relies on the activity of ten–eleven translocation (TET) enzymes. Paradoxically, in important biological contexts these antagonistic factors are co-expressed and ta...

Alternative Titles

Full title

Active turnover of DNA methylation during cell fate decisions

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2449178269

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2449178269

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/s41576-020-00287-8

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