Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The molecular function of Atg9, the sole transmembrane protein in the autophagosome-forming machinery, remains unknown. Atg9 colocalizes with Atg2 at the expanding edge of the isolation membrane (IM), where Atg2 receives phospholipids from the endoplasmic reticulum (ER). Here we report that yeast and human Atg9 are lipid scramblases that translocat...
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Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
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TN_cdi_proquest_miscellaneous_2454654834
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2454654834
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-020-00518-w
