Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by micr...
Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4
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Publisher
England: Nature Publishing Group
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English
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England: Nature Publishing Group
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The canonical model of agonist-stimulated phosphatidylinositol-3-OH kinase (PI3K)-Akt signalling proposes that PI3K is activated at the plasma membrane, where receptors are activated and phosphatidylinositol-4,5-bisphosphate is concentrated. Here we show that phosphatidylinositol-3,4,5-trisphosphate generation and activated Akt are instead largely...
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Full title
Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4
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TN_cdi_proquest_miscellaneous_2457303791
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2457303791
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-00596-4
