A highly heterogeneous mutational pattern in POEMS syndrome
A highly heterogeneous mutational pattern in POEMS syndrome
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Author / Creator
Chen, Jia , Gao, Xue-min , Zhao, Hao , Cai, Hao , Zhang, Lu , Cao, Xin-xin , Zhou, Dao-bin and Li, Jian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
POEMS syndrome is a rare plasma cell dyscrasia. Little is known about its pathogenesis and genetic features. We analyzed the mutational features of purified bone marrow plasma cells from 42 patients newly diagnosed with POEMS syndrome using a two-step strategy. Whole exome sequencing of ten patients showed a total of 170 somatic mutations in exonic...
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Full title
A highly heterogeneous mutational pattern in POEMS syndrome
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2466298168
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466298168
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-01101-4
