Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care
Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care
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Publisher
United States: Massachusetts Medical Society
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Language
English
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Publisher
United States: Massachusetts Medical Society
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Contents
Nothing has changed cancer therapy more in the past 5 to 10 years than the introduction of immune checkpoint inhibitors. In solid tumors, the activity of these agents is commonly linked to the presence of a hypermutated phenotype with the expression of tumor-specific neoantigens at the surface of cancer cells that can serve as targets for T cells....
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Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care
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TN_cdi_proquest_miscellaneous_2466769018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466769018
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMe2031294