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Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care

Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466769018

Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care

About this item

Full title

Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care

Author / Creator

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2020-12, Vol.383 (23), p.2283-2285

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

Nothing has changed cancer therapy more in the past 5 to 10 years than the introduction of immune checkpoint inhibitors. In solid tumors, the activity of these agents is commonly linked to the presence of a hypermutated phenotype with the expression of tumor-specific neoantigens at the surface of cancer cells that can serve as targets for T cells....

Alternative Titles

Full title

Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2466769018

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466769018

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMe2031294

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