Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis
Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In the adult hippocampus, synapses are constantly formed and eliminated
1
,
2
. However, the exact function of synapse elimination in the adult brain, and how it is regulated, are largely unknown. Here we show that astrocytic phagocytosis
3
is important for maintaining proper hippocampal synaptic connectivity and plasticity. By us...
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Full title
Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis
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TN_cdi_proquest_miscellaneous_2473400506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2473400506
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-03060-3