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SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2475088881

SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

About this item

Full title

SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

Publisher

Cham: Springer International Publishing

Journal title

Annals of surgical oncology, 2021-08, Vol.28 (8), p.4720-4732

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background
Anticancer drugs generate excessive reactive oxygen species (ROS), which can cause cell death. Cancer cells can resist this oxidative stress, but the mechanism of resistance and associations with chemoresistance are unclear. Here, we focused on Sirtuin 3 (SIRT3), a deacetylating mitochondrial enzyme, in oxidative stress resistance in...

Alternative Titles

Full title

SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2475088881

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2475088881

Other Identifiers

ISSN

1068-9265

E-ISSN

1534-4681

DOI

10.1245/s10434-020-09373-x

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