LCK senses asparagine for T cell activation
LCK senses asparagine for T cell activation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Amino acids are critical nutrients that contribute to metabolic and signalling pathways required to meet energy and biosynthetic demands in T cells. A new study now demonstrates that LCK can sense intracellular asparagine to support T cell receptor-mediated CD8
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T cell activation and effector responses to pathogens and tumours.
Alternative Titles
Full title
LCK senses asparagine for T cell activation
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2476561267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476561267
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-00621-6
