Stem-cell-derived human microglia transplanted into mouse brain to study human disease
Stem-cell-derived human microglia transplanted into mouse brain to study human disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Microglia are critically involved in complex neurological disorders with a strong genetic component, such as Alzheimer’s disease, Parkinson’s disease and frontotemporal dementia. Although mouse microglia can recapitulate aspects of human microglia physiology, they do not fully capture the human genetic aspects of disease and do not reproduce all hu...
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Full title
Stem-cell-derived human microglia transplanted into mouse brain to study human disease
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TN_cdi_proquest_miscellaneous_2476852067
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476852067
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-020-00447-4
