Chaperone-mediated autophagy sustains haematopoietic stem-cell function
Chaperone-mediated autophagy sustains haematopoietic stem-cell function
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The activation of mostly quiescent haematopoietic stem cells (HSCs) is a prerequisite for life-long production of blood cells
1
. This process requires major molecular adaptations to allow HSCs to meet the regulatory and metabolic requirements for cell division
2
–
4
. The mechanisms that govern cellular reprograming upon stem-cel...
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Full title
Chaperone-mediated autophagy sustains haematopoietic stem-cell function
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TN_cdi_proquest_miscellaneous_2478037737
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2478037737
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-03129-z