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Chaperone-mediated autophagy sustains haematopoietic stem-cell function

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2478037737

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

About this item

Full title

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2021-03, Vol.591 (7848), p.117-123

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The activation of mostly quiescent haematopoietic stem cells (HSCs) is a prerequisite for life-long production of blood cells
1
. This process requires major molecular adaptations to allow HSCs to meet the regulatory and metabolic requirements for cell division
2

4
. The mechanisms that govern cellular reprograming upon stem-cel...

Alternative Titles

Full title

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2478037737

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2478037737

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-03129-z

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