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The roles of Polycomb repressive complexes in mammalian development and cancer

The roles of Polycomb repressive complexes in mammalian development and cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2501849563

The roles of Polycomb repressive complexes in mammalian development and cancer

About this item

Full title

The roles of Polycomb repressive complexes in mammalian development and cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2021-05, Vol.22 (5), p.326-345

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

More than 80 years ago, the first Polycomb-related phenotype was identified in
Drosophila melanogaster
. Later, a group of diverse genes collectively called Polycomb group (PcG) genes were identified based on common mutant phenotypes. PcG proteins, which are well-conserved in animals, were originally characterized as negative regulators of ge...

Alternative Titles

Full title

The roles of Polycomb repressive complexes in mammalian development and cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2501849563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2501849563

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/s41580-021-00341-1

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