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Genome folding through loop extrusion by SMC complexes

Genome folding through loop extrusion by SMC complexes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2506285294

Genome folding through loop extrusion by SMC complexes

About this item

Full title

Genome folding through loop extrusion by SMC complexes

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2021-07, Vol.22 (7), p.445-464

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genomic DNA is folded into loops and topologically associating domains (TADs), which serve important structural and regulatory roles. It has been proposed that these genomic structures are formed by a loop extrusion process, which is mediated by structural maintenance of chromosomes (SMC) protein complexes. Recent single-molecule studies have shown...

Alternative Titles

Full title

Genome folding through loop extrusion by SMC complexes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2506285294

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2506285294

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/s41580-021-00349-7

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