Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer’s...
Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer’s disease
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Author / Creator
Tian, Ding-Yuan , Cheng, Yuan , Zhuang, Zhen-Qian , He, Chen-Yang , Pan, Qian-Guang , Tang, Mao-Zhi , Hu, Xue-Lian , Shen, Ying-Ying , Wang, Ye-Ran , Chen, Si-Han , Sun, Hao-Lun , Sun, Pu-Yang , Yu, Zhong-Yuan , Fan, Dong-Yu , Bu, Xian-Le , Tan, Cheng-Rong , Zeng, Gui-Hua , Wang, Jun , Zhao, Hong-Wen and Wang, Yan-Jiang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Amyloid-β (Aβ) accumulation in the brain is a pivotal event in the pathogenesis of Alzheimer’s disease (AD), and its clearance from the brain is impaired in sporadic AD. Previous studies suggest that approximately half of the Aβ produced in the brain is cleared by transport into the periphery. However, the mechanism and pathophysiological significa...
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Full title
Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer’s disease
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Record Identifier
TN_cdi_proquest_miscellaneous_2510250454
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2510250454
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-021-01073-6
