Lineage tracing of human development through somatic mutations
Lineage tracing of human development through somatic mutations
About this item
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Author / Creator
Spencer Chapman, Michael , Ranzoni, Anna Maria , Myers, Brynelle , Williams, Nicholas , Coorens, Tim H. H. , Mitchell, Emily , Butler, Timothy , Dawson, Kevin J. , Hooks, Yvette , Moore, Luiza , Nangalia, Jyoti , Robinson, Philip S. , Yoshida, Kenichi , Hook, Elizabeth , Campbell, Peter J. and Cvejic, Ana
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The ontogeny of the human haematopoietic system during fetal development has previously been characterized mainly through careful microscopic observations
1
. Here we reconstruct a phylogenetic tree of blood development using whole-genome sequencing of 511 single-cell-derived haematopoietic colonies from healthy human fetuses at 8 and 18 week...
Alternative Titles
Full title
Lineage tracing of human development through somatic mutations
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2526306808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2526306808
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03548-6
