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Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors...

Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2551579617

Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis

About this item

Full title

Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis

Publisher

New York: Springer US

Journal title

Investigational new drugs, 2021-12, Vol.39 (6), p.1732-1741

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Summary
Objectives
In
EGFR
-mutated non-small cell lung cancer (NSCLC) patients, approximately 80–90% of leptomeningeal metastasis (LM) develops after failed initial treatment with epidermal growth factor receptor (
EGFR
) tyrosine kinase inhibitor (EGFR-TKI). However, the efficacy of rechallenging with previously administered EGF...

Alternative Titles

Full title

Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2551579617

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2551579617

Other Identifiers

ISSN

0167-6997

E-ISSN

1573-0646

DOI

10.1007/s10637-021-01140-3

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