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Investigating the natural history and prognostic nature of NTRK gene fusions in solid tumors

Investigating the natural history and prognostic nature of NTRK gene fusions in solid tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2557547819

Investigating the natural history and prognostic nature of NTRK gene fusions in solid tumors

About this item

Full title

Investigating the natural history and prognostic nature of NTRK gene fusions in solid tumors

Publisher

New York: Springer US

Journal title

Investigational new drugs, 2022-02, Vol.40 (1), p.157-162

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Summary
Background
. Several TRK inhibitors have demonstrated clinical efficacy in patients with solid tumors harboring NTRK gene fusions. However, the natural history and prognostic implications of NTRK fusions in solid tumors remain unknown.
Methods
. A cohort of 77 MD Anderson Cancer Center patients (MDACC) with NTRK gene fusions was...

Alternative Titles

Full title

Investigating the natural history and prognostic nature of NTRK gene fusions in solid tumors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2557547819

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2557547819

Other Identifiers

ISSN

0167-6997

E-ISSN

1573-0646

DOI

10.1007/s10637-021-01157-8

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