Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alteratio...
Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial
About this item
Full title
Author / Creator
de Bono, Johann S, Prof , Mehra, Niven, PhD , Scagliotti, Giorgio V, Prof , Castro, Elena, PhD , Dorff, Tanya, MD , Stirling, Adam, MD , Stenzl, Arnulf, Prof , Fleming, Mark T, MD , Higano, Celestia S, MD , Saad, Fred, MD , Buttigliero, Consuelo, PhD , van Oort, Inge M, PhD , Laird, A Douglas, PhD , Mata, Marielena, PhD , Chen, Hsiang-Chun, PhD , Healy, Cynthia G, BS , Czibere, Akos, MD and Fizazi, Karim, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
SummaryBackgroundPoly(ADP-ribose) polymerase (PARP) inhibitors have antitumour activity against metastatic castration-resistant prostate cancers with DNA damage response (DDR) alterations in genes involved directly or indirectly in homologous recombination repair (HRR). In this study, we assessed the PARP inhibitor talazoparib in metastatic castrat...
Alternative Titles
Full title
Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Mehra, Niven, PhD
Scagliotti, Giorgio V, Prof
Castro, Elena, PhD
Dorff, Tanya, MD
Stirling, Adam, MD
Stenzl, Arnulf, Prof
Fleming, Mark T, MD
Higano, Celestia S, MD
Saad, Fred, MD
Buttigliero, Consuelo, PhD
van Oort, Inge M, PhD
Laird, A Douglas, PhD
Mata, Marielena, PhD
Chen, Hsiang-Chun, PhD
Healy, Cynthia G, BS
Czibere, Akos, MD
Fizazi, Karim, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2561489202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2561489202
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(21)00376-4
