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ArticlesPeer ReviewedFull Text
Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial
Author / Creator:de Bono, Johann S, Prof ; Mehra, Niven, PhD ; Scagliotti, Giorgio V, Prof ; Castro, Elena, PhD ; Dorff, Tanya, MD ; Stirling, Adam, MD ; Stenzl, Arnulf, Prof ; Fleming, Mark T, MD ; Higano, Celestia S, MD ; Saad, Fred, MD ; Buttigliero, Consuelo, PhD ; van Oort, Inge M, PhD ; Laird, A Douglas, PhD ; Mata, Marielena, PhD ; Chen, Hsiang-Chun, PhD ; Healy, Cynthia G, BS ; Czibere, Akos, MD ; Fizazi, Karim, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-09, Vol.22 (9), p.1250-1264
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ArticlesPeer ReviewedFull Text
Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a ran...
Author / Creator:Ryan, Charles J, Prof ; Smith, Matthew R, Prof ; Fizazi, Karim, Prof ; Saad, Fred, Prof ; Mulders, Peter F A, Prof ; Sternberg, Cora N, MD ; Miller, Kurt, Prof ; Logothetis, Christopher J, Prof ; Shore, Neal D, MD ; Small, Eric J, Prof ; Carles, Joan, MD ; Flaig, Thomas W, MD ; Taplin, Mary-Ellen, MD ; Higano, Celestia S, Prof ; de Souza, Paul, Prof ; de Bono, Johann S, Prof ; Griffin, Thomas W, MD ; De Porre, Peter, MD ; Yu, Margaret K, MD ; Park, Youn C, PhD ; Li, Jinhui, PhD ; Kheoh, Thian, PhD ; Naini, Vahid, PharmD ; Molina, Arturo, MD ; Rathkopf, Dana E, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-02, Vol.16 (2), p.152-160
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ArticlesPeer ReviewedFull Text
Sequencing of agents in castration-resistant prostate cancer
Author / Creator:Lorente, David, MD ; Mateo, Joaquin, MD ; Perez-Lopez, Raquel, MD ; de Bono, Johann S, Prof ; Attard, Gerhardt, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-06, Vol.16 (6), p.e279-e292
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ArticlesPeer ReviewedFull Text
The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial
Author / Creator:Sandhu, Shahneen K, MD ; Schelman, William R, MD ; Wilding, George, MD ; Moreno, Victor, MD ; Baird, Richard D, PhD ; Miranda, Susana, BSc ; Hylands, Lucy, BSc ; Riisnaes, Ruth, FIBMS ; Forster, Martin, PhD ; Omlin, Aurelius, MD ; Kreischer, Nathan, MSc ; Thway, Khin, MD ; Gevensleben, Heidrun, MD ; Sun, Linda, PhD ; Loughney, John, PhD ; Chatterjee, Manash, PhD ; Toniatti, Carlo, PhD ; Carpenter, Christopher L, MD ; Iannone, Robert, MD ; Kaye, Stan B, Prof ; de Bono, Johann S, Prof ; Wenham, Robert M
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-08, Vol.14 (9), p.882-892
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ArticlesPeer ReviewedFull Text
Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1–2 trial
Author / Creator:de Bono, Johann S, Prof ; Concin, Nicole, Prof ; Hong, David S, MD ; Thistlethwaite, Fiona C, MBBChir ; Machiels, Jean-Pascal, Prof ; Arkenau, Hendrik-Tobias, MD ; Plummer, Ruth, Prof ; Jones, Robert Hugh, MRCP ; Nielsen, Dorte, Prof ; Windfeld, Kristian, PhD ; Ghatta, Srinivas, PhD ; Slomovitz, Brian M, MD ; Spicer, James F, Prof ; Yachnin, Jeffrey, MD ; Ang, Joo Ern, MRCP ; Mau-Sørensen, Paul Morten, MD ; Forster, Martin David, FRCP ; Collins, Dearbhaile, MBBS ; Dean, Emma, MD ; Rangwala, Reshma A, MD ; Lassen, Ulrik, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2019-03, Vol.20 (3), p.383-393
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ArticlesPeer ReviewedFull Text
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
Author / Creator:Fizazi, Karim, Prof Dr ; Scher, Howard I, Prof ; Molina, Arturo, MD ; Logothetis, Christopher J, Prof ; Chi, Kim N, MD ; Jones, Robert J, PhD ; Staffurth, John N, MD ; North, Scott, MD ; Vogelzang, Nicholas J, MD ; Saad, Fred, Prof ; Mainwaring, Paul, MD ; Harland, Stephen, MD ; Goodman, Oscar B, MD ; Sternberg, Cora N, MD ; Li, Jin Hui, PhD ; Kheoh, Thian, PhD ; Haqq, Christopher M, MD ; de Bono, Johann S, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-10, Vol.13 (10), p.983-992
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ArticlesPeer ReviewedFull Text
Effect of enzalutamide on time to first skeletal-related event, pain, and quality of life in men with castration-resistant prostate cancer: results from the randomised, phase 3 AFFIRM trial
Author / Creator:Fizazi, Karim, Prof ; Scher, Howard I, Prof ; Miller, Kurt, Prof ; Basch, Ethan, MD ; Sternberg, Cora N, MD ; Cella, David, Prof ; Forer, David, MSc ; Hirmand, Mohammad, MD ; de Bono, Johann S, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-09, Vol.15 (10), p.1147-1156
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ArticlesPeer ReviewedFull Text
Effect of enzalutamide on health-related quality of life, pain, and skeletal-related events in asymptomatic and minimally symptomatic, chemotherapy-naive patients with metastatic castration-resistant...
Author / Creator:Loriot, Yohann, Dr ; Miller, Kurt, Prof ; Sternberg, Cora N, Prof ; Fizazi, Karim, Prof ; De Bono, Johann S, Prof ; Chowdhury, Simon, PhD ; Higano, Celestia S, MD ; Noonberg, Sarah, MD ; Holmstrom, Stefan, MSc ; Mansbach, Harry, MD ; Perabo, Frank G, MD ; Phung, De, BSc ; Ivanescu, Cristina, PhD ; Skaltsa, Konstantina, PhD ; Beer, Tomasz M, Prof ; Tombal, Bertrand, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.509-521
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ArticlesPeer ReviewedFull Text
Intermittent schedules of the oral RAF–MEK inhibitor CH5126766/VS-6766 in patients with RAS/RAF-mutant solid tumours and multiple myeloma: a single-centre, open-label, phase 1 dose-escalation and bask...
Author / Creator:Guo, Christina, FRACP ; Chénard-Poirier, Maxime, FRCPC ; Roda, Desamparados, MD ; de Miguel, Maria, MD ; Harris, Samuel J, FRACP ; Candilejo, Irene Moreno, MD ; Sriskandarajah, Priya, PhD ; Xu, Wen, FRACP ; Scaranti, Mariana, MD ; Constantinidou, Anastasia, MRCP ; King, Jenny, MSc ; Parmar, Mona, PhD ; Turner, Alison J, PhD ; Carreira, Suzanne, PhD ; Riisnaes, Ruth, FIBMS ; Finneran, Laura, MSc ; Hall, Emma, Prof ; Ishikawa, Yuji, PhD ; Nakai, Kiyohiko, MS ; Tunariu, Nina, FRCR ; Basu, Bristi, FRCP ; Kaiser, Martin, MD ; Lopez, Juanita Suzanne, MRCP ; Minchom, Anna, MD ; de Bono, Johann S, Prof ; Banerji, Udai, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-11, Vol.21 (11), p.1478-1488
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ArticlesPeer ReviewedFull Text
Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: explorat...
Author / Creator:Logothetis, Christopher J, Prof ; Basch, Ethan, MD ; Molina, Arturo, MD ; Fizazi, Karim, Prof ; North, Scott A, MD ; Chi, Kim N, MD ; Jones, Robert J, MD ; Goodman, Oscar B, MD ; Mainwaring, Paul N, MD ; Sternberg, Cora N, MD ; Efstathiou, Eleni, MD ; Gagnon, Dennis D, MA ; Rothman, Margaret, PhD ; Hao, Yanni, PhD ; Liu, Cameron S, PhD ; Kheoh, Thian S, PhD ; Haqq, Christopher M, MD ; Scher, Howard I, Prof ; de Bono, Johann S, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-12, Vol.13 (12), p.1210-1217
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ArticlesPeer ReviewedFull Text
Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial
Author / Creator:Chi, Kim N, Prof ; Higano, Celestia S, MD ; Blumenstein, Brent, PhD ; Ferrero, Jean-Marc, Prof ; Reeves, James, MD ; Feyerabend, Susan, MD ; Gravis, Gwenaelle, MD ; Merseburger, Axel S, Prof ; Stenzl, Arnulf, Prof ; Bergman, Andries M, MD ; Mukherjee, Som D, MD ; Zalewski, Pawel, MD ; Saad, Fred, Prof ; Jacobs, Cindy, MD ; Gleave, Martin, Prof ; de Bono, Johann S, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-04, Vol.18 (4), p.473-485
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ArticlesPeer ReviewedFull Text
Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study
Author / Creator:Olmos, David, MD ; Brewer, Daniel, PhD ; Clark, Jeremy, PhD ; Danila, Daniel C, MD ; Parker, Chris, MD ; Attard, Gerhardt, MD ; Fleisher, Martin, MD ; Reid, Alison HM, MD ; Castro, Elena, MD ; Sandhu, Shahneen K, MD ; Barwell, Lorraine, MS ; Oommen, Nikhil Babu, MD ; Carreira, Suzanne, PhD ; Drake, Charles G, MD ; Jones, Robert, MD ; Cooper, Colin S, Prof ; Scher, Howard I, Prof ; de Bono, Johann S, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-11, Vol.13 (11), p.1114-1124
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ArticlesPeer ReviewedFull Text
Prostate cancer
Author / Creator:Attard, Gerhardt, MD ; Parker, Chris, FRCR ; Eeles, Ros A, FRCR ; Schröder, Fritz, Prof ; Tomlins, Scott A, MD ; Tannock, Ian, MD ; Drake, Charles G, MD ; de Bono, Johann S, Prof
Journal title:The Lancet (British edition), 2016, Vol.387 (10013), p.70-82
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Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial

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Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a ran...

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Sequencing of agents in castration-resistant prostate cancer

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The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial

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Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1–2 trial

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Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study

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Effect of enzalutamide on time to first skeletal-related event, pain, and quality of life in men with castration-resistant prostate cancer: results from the randomised, phase 3 AFFIRM trial

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Effect of enzalutamide on health-related quality of life, pain, and skeletal-related events in asymptomatic and minimally symptomatic, chemotherapy-naive patients with metastatic castration-resistant...

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Intermittent schedules of the oral RAF–MEK inhibitor CH5126766/VS-6766 in patients with RAS/RAF-mutant solid tumours and multiple myeloma: a single-centre, open-label, phase 1 dose-escalation and bask...

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Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: explorat...

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Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial

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Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study

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