Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or ref...
Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study
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Full title
Author / Creator
Usmani, Saad Z , Garfall, Alfred L , van de Donk, Niels W C J , Nahi, Hareth , San-Miguel, Jesus F , Oriol, Albert , Rosinol, Laura , Chari, Ajai , Bhutani, Manisha , Karlin, Lionel , Benboubker, Lotfi , Pei, Lixia , Verona, Raluca , Girgis, Suzette , Stephenson, Tara , Elsayed, Yusri , Infante, Jeffrey , Goldberg, Jenna D , Banerjee, Arnob , Mateos, María-Victoria and Krishnan, Amrita
Publisher
London: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
There is a need for novel therapies for relapsed or refractory multiple myeloma, and B-cell maturation antigen (BCMA) is a validated target. Teclistamab is a bispecific antibody that binds BCMA and CD3 to redirect T cells to multiple myeloma cells. The aim of the MajesTEC-1 study was to evaluate the safety, tolerability, and preliminary efficacy of...
Alternative Titles
Full title
Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study
Authors, Artists and Contributors
Author / Creator
Garfall, Alfred L
van de Donk, Niels W C J
Nahi, Hareth
San-Miguel, Jesus F
Oriol, Albert
Rosinol, Laura
Chari, Ajai
Bhutani, Manisha
Karlin, Lionel
Benboubker, Lotfi
Pei, Lixia
Verona, Raluca
Girgis, Suzette
Stephenson, Tara
Elsayed, Yusri
Infante, Jeffrey
Goldberg, Jenna D
Banerjee, Arnob
Mateos, María-Victoria
Krishnan, Amrita
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2561489424
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2561489424
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(21)01338-6