Apalutamide plus abiraterone acetate and prednisone versus placebo plus abiraterone and prednisone i...
Apalutamide plus abiraterone acetate and prednisone versus placebo plus abiraterone and prednisone in metastatic, castration-resistant prostate cancer (ACIS): a randomised, placebo-controlled, double-blind, multinational, phase 3 study
About this item
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Author / Creator
Saad, Fred , Efstathiou, Eleni , Attard, Gerhardt , Flaig, Thomas W , Franke, Fabio , Goodman, Oscar B , Oudard, Stéphane , Steuber, Thomas , Suzuki, Hiroyoshi , Wu, Daphne , Yeruva, Kesav , De Porre, Peter , Brookman-May, Sabine , Li, Susan , Li, Jinhui , Thomas, Shibu , Bevans, Katherine B , Mundle, Suneel D , McCarthy, Sharon A , Rathkopf, Dana E and ACIS Investigators
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
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Scope and Contents
Contents
The majority of patients with metastatic castration-resistant prostate cancer (mCRPC) will have disease progression of a uniformly fatal disease. mCRPC is driven by both activated androgen receptors and elevated intratumoural androgens; however, the current standard of care is therapy that targets a single androgen signalling mechanism. We aimed to...
Alternative Titles
Full title
Apalutamide plus abiraterone acetate and prednisone versus placebo plus abiraterone and prednisone in metastatic, castration-resistant prostate cancer (ACIS): a randomised, placebo-controlled, double-blind, multinational, phase 3 study
Authors, Artists and Contributors
Author / Creator
Efstathiou, Eleni
Attard, Gerhardt
Flaig, Thomas W
Franke, Fabio
Goodman, Oscar B
Oudard, Stéphane
Steuber, Thomas
Suzuki, Hiroyoshi
Wu, Daphne
Yeruva, Kesav
De Porre, Peter
Brookman-May, Sabine
Li, Susan
Li, Jinhui
Thomas, Shibu
Bevans, Katherine B
Mundle, Suneel D
McCarthy, Sharon A
Rathkopf, Dana E
ACIS Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2579088104
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579088104
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(21)00402-2
