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Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2601489309

Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

About this item

Full title

Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

Publisher

London: Nature Publishing Group UK

Journal title

Nature biomedical engineering, 2022-04, Vol.6 (4), p.421-434

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pacemaker cells can be differentiated from stem cells or transdifferentiated from quiescent mature cardiac cells via genetic manipulation. Here we show that the exposure of rat quiescent ventricular cardiomyocytes to a silk-fibroin hydrogel activates the direct conversion of the quiescent cardiomyocytes to pacemaker cardiomyocytes by inducing the e...

Alternative Titles

Full title

Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2601489309

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2601489309

Other Identifiers

ISSN

2157-846X

E-ISSN

2157-846X

DOI

10.1038/s41551-021-00812-y

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