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Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-p...

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Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2619217039

Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway

About this item

Full title

Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway

Author / Creator

Kawabata, Hidemasa , Ono, Yusuke , Tamamura, Nobue , Oyama, Kyohei , Ueda, Jun , Sato, Hiroki , Takahashi, Kenji , Taniue, Kenzui , Okada, Tetsuhiro , Fujibayashi, Syugo , Hayashi, Akihiro , Goto, Takuma , Enomoto, Katsuro , Konishi, Hiroaki , Fujiya, Mikihiro , Miyakawa, Keita , Tanino, Mishie , Nishikawa, Yuji , Koga, Daisuke , Watanabe, Tsuyoshi , Maeda, Chiho , Karasaki, Hidenori , Liss, Andrew S. , Mizukami, Yusuke and Okumura, Toshikatsu

Publisher

Singapore: Springer Singapore

Journal title

Journal of gastroenterology, 2022-03, Vol.57 (3), p.208-220

Language

English

Formats

Articles

Publication information

Publisher

Singapore: Springer Singapore

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Background
Mutations in
GNAS
drive pancreatic tumorigenesis and frequently occur in intraductal papillary mucinous neoplasm (IPMN); however, their value as a therapeutic target is yet to be determined. This study aimed at evaluating the involvement of mutant
GNAS
in tumor aggressiveness in established pancreatic cancer.
Methods

Alternative Titles

Full title

Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2619217039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2619217039

Other Identifiers

ISSN

0944-1174

E-ISSN

1435-5922

DOI

10.1007/s00535-021-01846-4

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