The acidic domain of Hmga2 and the domain’s linker region are critical for driving self-renewal of h...
The acidic domain of Hmga2 and the domain’s linker region are critical for driving self-renewal of hematopoietic stem cell
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Publisher
Singapore: Springer Singapore
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Language
English
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Publisher
Singapore: Springer Singapore
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Contents
High mobility group AT-hook 2 (Hmga2) is a chromatin modifier protein that plays a critical role in fetal development and leukemia propagation by binding to chromatin and DNA via its AT-hook domains. However, the molecular mechanisms by which Hmga2 activates the expression of target genes to drive the self-renewal of hematopoietic stem cells (HSCs)...
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Full title
The acidic domain of Hmga2 and the domain’s linker region are critical for driving self-renewal of hematopoietic stem cell
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TN_cdi_proquest_miscellaneous_2622473503
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2622473503
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ISSN
0925-5710
E-ISSN
1865-3774
DOI
10.1007/s12185-021-03274-9
