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Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers:...

Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers:...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2629385625

Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers: a cross-over design — The BIND study

About this item

Full title

Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers: a cross-over design — The BIND study

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of clinical pharmacology, 2022-05, Vol.78 (5), p.839-845

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Polystyrene sulfonate is used for binding potassium in patients with chronic kidney disease (CKD). Because of its binding properties, it can potentially bind other medications and thereby decrease their bioavailability and effectiveness. Amitriptyline, often used by CKD patients for neuropathic pain, shows significant binding to polystyr...

Alternative Titles

Full title

Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers: a cross-over design — The BIND study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2629385625

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2629385625

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-022-03283-5

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