The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics
The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Many drugs that target amyloid-β (Aβ) in Alzheimer disease (AD) have failed to demonstrate clinical efficacy. However, four anti-Aβ antibodies have been shown to mediate the removal of amyloid plaque from brains of patients with AD, and the FDA has recently granted accelerated approval to one of these, aducanumab, using reduction of amyloid plaque...
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Full title
The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics
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TN_cdi_proquest_miscellaneous_2630919099
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2630919099
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-022-00391-w
