Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a fi...
Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme
About this item
Full title
Author / Creator
Mead, Simon , Khalili-Shirazi, Azadeh , Potter, Caroline , Mok, Tzehow , Nihat, Akin , Hyare, Harpreet , Canning, Stephanie , Schmidt, Christian , Campbell, Tracy , Darwent, Lee , Muirhead, Nicola , Ebsworth, Nicolette , Hextall, Patrick , Wakeling, Madeleine , Linehan, Jacqueline , Libri, Vincenzo , Williams, Bryan , Jaunmuktane, Zane , Brandner, Sebastian , Rudge, Peter and Collinge, John
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Human prion diseases, including Creutzfeldt–Jakob disease (CJD), are rapidly progressive, invariably fatal neurodegenerative conditions with no effective therapies. Their pathogenesis involves the obligate recruitment of cellular prion protein (PrPC) into self-propagating multimeric assemblies or prions. Preclinical studies have firmly validated th...
Alternative Titles
Full title
Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme
Authors, Artists and Contributors
Author / Creator
Khalili-Shirazi, Azadeh
Potter, Caroline
Mok, Tzehow
Nihat, Akin
Hyare, Harpreet
Canning, Stephanie
Schmidt, Christian
Campbell, Tracy
Darwent, Lee
Muirhead, Nicola
Ebsworth, Nicolette
Hextall, Patrick
Wakeling, Madeleine
Linehan, Jacqueline
Libri, Vincenzo
Williams, Bryan
Jaunmuktane, Zane
Brandner, Sebastian
Rudge, Peter
Collinge, John
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2640995891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2640995891
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(22)00082-5
