An engineered prime editor with enhanced editing efficiency in plants
An engineered prime editor with enhanced editing efficiency in plants
About this item
Full title
Author / Creator
Zong, Yuan , Liu, Yijing , Xue, Chenxiao , Li, Boshu , Li, Xiangyang , Wang, Yanpeng , Li, Ji , Liu, Guanwen , Huang, Xingxu , Cao, Xiaofeng and Gao, Caixia
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Prime editing is a versatile genome-editing technology, but it suffers from low editing efficiency. In the present study, we introduce optimized prime editors with substantially improved editing efficiency. We engineered the Moloney–murine leukemia virus reverse transcriptase by removing its ribonuclease H domain and incorporated a viral nucleocaps...
Alternative Titles
Full title
An engineered prime editor with enhanced editing efficiency in plants
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2644023704
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2644023704
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01254-w
