Synonymous mutations in representative yeast genes are mostly strongly non-neutral
Synonymous mutations in representative yeast genes are mostly strongly non-neutral
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Synonymous mutations in protein-coding genes do not alter protein sequences and are thus generally presumed to be neutral or nearly neutral
1
–
5
. Here, to experimentally verify this presumption, we constructed 8,341 yeast mutants each carrying a synonymous, nonsynonymous or nonsense mutation in one of 21 endogenous genes with diverse...
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Synonymous mutations in representative yeast genes are mostly strongly non-neutral
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TN_cdi_proquest_miscellaneous_2674754764
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2674754764
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04823-w
