Targeting telomeres: advances in telomere maintenance mechanism-specific cancer therapies
Targeting telomeres: advances in telomere maintenance mechanism-specific cancer therapies
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cancer cells establish replicative immortality by activating a telomere-maintenance mechanism (TMM), be it telomerase or the alternative lengthening of telomeres (ALT) pathway. Targeting telomere maintenance represents an intriguing opportunity to treat the vast majority of all cancer types. Whilst telomerase inhibitors have historically been heral...
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Targeting telomeres: advances in telomere maintenance mechanism-specific cancer therapies
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TN_cdi_proquest_miscellaneous_2685444570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2685444570
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ISSN
1474-175X,1474-1768
E-ISSN
1474-1768
DOI
10.1038/s41568-022-00490-1
