Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse develo...
Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development
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Author / Creator
Fei, Lijiang , Chen, Haide , Ma, Lifeng , E, Weigao , Wang, Renying , Fang, Xing , Zhou, Ziming , Sun, Huiyu , Wang, Jingjing , Jiang, Mengmeng , Wang, Xinru , Yu, Chengxuan , Mei, Yuqing , Jia, Danmei , Zhang, Tingyue , Han, Xiaoping and Guo, Guoji
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Waddington’s epigenetic landscape is a metaphor frequently used to illustrate cell differentiation. Recent advances in single-cell genomics are altering our understanding of the Waddington landscape, yet the molecular mechanisms of cell-fate decisions remain poorly understood. We constructed a cell landscape of mouse lineage differentiation during...
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Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development
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TN_cdi_proquest_miscellaneous_2688521293
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2688521293
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01118-8