Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for a...
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
About this item
Full title
Author / Creator
Palmer, Christine D. , Rappaport, Amy R. , Davis, Matthew J. , Hart, Meghan G. , Scallan, Ciaran D. , Hong, Sue-Jean , Gitlin, Leonid , Kraemer, Lauren D. , Kounlavouth, Sonia , Yang, Aaron , Smith, Lindsey , Schenk, Desiree , Skoberne, Mojca , Taquechel, Kiara , Marrali, Martina , Jaroslavsky, Jason R. , Nganje, Charmaine N. , Maloney, Elizabeth , Zhou, Rita , Navarro-Gomez, Daniel , Greene, Adrienne C. , Grotenbreg, Gijsbert , Greer, Renee , Blair, Wade , Cao, Minh Duc , Chan, Shawn , Bae, Kyounghwa , Spira, Alexander I. , Roychowdhury, Sameek , Carbone, David P. , Henick, Brian S. , Drake, Charles G. , Solomon, Benjamin J. , Ahn, Daniel H. , Mahipal, Amit , Maron, Steve B. , Johnson, Benny , Rousseau, Raphael , Yelensky, Roman , Liao, Chih-Yi , Catenacci, Daniel V. T. , Allen, Andrew , Ferguson, Andrew R. and Jooss, Karin
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Checkpoint inhibitor (CPI) therapies provide limited benefit to patients with tumors of low immune reactivity. T cell-inducing vaccines hold promise to exert long-lasting disease control in combination with CPI therapy. Safety, tolerability and recommended phase 2 dose (RP2D) of an individualized, heterologous chimpanzee adenovirus (ChAd68) and sel...
Alternative Titles
Full title
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
Authors, Artists and Contributors
Author / Creator
Rappaport, Amy R.
Davis, Matthew J.
Hart, Meghan G.
Scallan, Ciaran D.
Hong, Sue-Jean
Gitlin, Leonid
Kraemer, Lauren D.
Kounlavouth, Sonia
Yang, Aaron
Smith, Lindsey
Schenk, Desiree
Skoberne, Mojca
Taquechel, Kiara
Marrali, Martina
Jaroslavsky, Jason R.
Nganje, Charmaine N.
Maloney, Elizabeth
Zhou, Rita
Navarro-Gomez, Daniel
Greene, Adrienne C.
Grotenbreg, Gijsbert
Greer, Renee
Blair, Wade
Cao, Minh Duc
Chan, Shawn
Bae, Kyounghwa
Spira, Alexander I.
Roychowdhury, Sameek
Carbone, David P.
Henick, Brian S.
Drake, Charles G.
Solomon, Benjamin J.
Ahn, Daniel H.
Mahipal, Amit
Maron, Steve B.
Johnson, Benny
Rousseau, Raphael
Yelensky, Roman
Liao, Chih-Yi
Catenacci, Daniel V. T.
Allen, Andrew
Ferguson, Andrew R.
Jooss, Karin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2702975594
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2702975594
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01937-6
