A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and poten...
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
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Author / Creator
Zhou, Yadi , Liu, Yuan , Gupta, Shagun , Paramo, Mauricio I. , Hou, Yuan , Mao, Chengsheng , Luo, Yuan , Judd, Julius , Wierbowski, Shayne , Bertolotti, Marta , Nerkar, Mriganka , Jehi, Lara , Drayman, Nir , Nicolaescu, Vlad , Gula, Haley , Tay, Savaş , Randall, Glenn , Wang, Peihui , Lis, John T. , Feschotte, Cédric , Erzurum, Serpil C. , Cheng, Feixiong and Yu, Haiyuan
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Studying viral–host protein–protein interactions can facilitate the discovery of therapies for viral infection. We use high-throughput yeast two-hybrid experiments and mass spectrometry to generate a comprehensive SARS-CoV-2–human protein–protein interactome network consisting of 739 high-confidence binary and co-complex interactions, validating 21...
Alternative Titles
Full title
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Authors, Artists and Contributors
Author / Creator
Liu, Yuan
Gupta, Shagun
Paramo, Mauricio I.
Hou, Yuan
Mao, Chengsheng
Luo, Yuan
Judd, Julius
Wierbowski, Shayne
Bertolotti, Marta
Nerkar, Mriganka
Jehi, Lara
Drayman, Nir
Nicolaescu, Vlad
Gula, Haley
Tay, Savaş
Randall, Glenn
Wang, Peihui
Lis, John T.
Feschotte, Cédric
Erzurum, Serpil C.
Cheng, Feixiong
Yu, Haiyuan
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2723815322
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2723815322
Other Identifiers
ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01474-0
