Log in to save to my catalogue

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2728467377

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

About this item

Full title

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2022-11, Vol.19 (11), p.1403-1410

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

RNA labeling in situ has enormous potential to visualize transcripts and quantify their levels in single cells, but it remains challenging to produce high levels of signal while also enabling multiplexed detection of multiple RNA species simultaneously. Here, we describe clampFISH 2.0, a method that uses an inverted padlock design to efficiently de...

Alternative Titles

Full title

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2728467377

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2728467377

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/s41592-022-01653-6

How to access this item