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Functional antibodies exhibit light chain coherence

Functional antibodies exhibit light chain coherence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2729519386

Functional antibodies exhibit light chain coherence

About this item

Full title

Functional antibodies exhibit light chain coherence

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2022-11, Vol.611 (7935), p.352-357

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The vertebrate adaptive immune system modifies the genome of individual B cells to encode antibodies that bind particular antigens
1
. In most mammals, antibodies are composed of heavy and light chains that are generated sequentially by recombination of V, D (for heavy chains), J and C gene segments. Each chain contains three complementarity-...

Alternative Titles

Full title

Functional antibodies exhibit light chain coherence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2729519386

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2729519386

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-022-05371-z

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