Novel mannich-based derivative of 2-mercaptobenzimidazole (AK7): a new candidate for the treatment o...
Novel mannich-based derivative of 2-mercaptobenzimidazole (AK7): a new candidate for the treatment of inflammatory arthritis owing to its NF-κB1 inhibitory potential
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Publisher
Germany
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Language
English
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Publisher
Germany
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Contents
This study investigated the anti-arthritic potential of novel mannich-based derivatives of 2-mercaptobenzimidazole (AK7 and AK9) in rats. The compounds were characterized by NMR and FTIR spectroscopies and their acute anti-inflammatory effects were measured by carrageenan (CRG)-induced paw edema model. The most potent doses of AK7 and AK9 were subs...
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Full title
Novel mannich-based derivative of 2-mercaptobenzimidazole (AK7): a new candidate for the treatment of inflammatory arthritis owing to its NF-κB1 inhibitory potential
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TN_cdi_proquest_miscellaneous_2754047026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2754047026
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ISSN
1432-1912
E-ISSN
1432-1912
DOI
10.1007/s00210-022-02359-4
