Translational perspectives from TSHR, MCT8 and TRα research
Translational perspectives from TSHR, MCT8 and TRα research
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In 2022, the activation mechanism of TSH receptor (TSHR) by TSH and autoantibodies was demonstrated, monocarboxylate transporter 8 (MCT8) deficiency was corrected with gene therapy in mice and mutant thyroid hormone receptor α (TRα) was activated with a synthetic ligand. These results offer translational perspectives for patients with common and ra...
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Translational perspectives from TSHR, MCT8 and TRα research
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TN_cdi_proquest_miscellaneous_2755578718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2755578718
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ISSN
1759-5029
E-ISSN
1759-5037
DOI
10.1038/s41574-022-00785-1
