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Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α...

Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2769373574

Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

About this item

Full title

Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2023-02, Vol.26 (2), p.213-225

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cell-to-cell transmission and subsequent amplification of pathological proteins promote neurodegenerative disease progression. Most research on this has focused on pathological protein seeds, but how their normal counterparts, which are converted to pathological forms during transmission, regulate transmission is less understood. Here we show in cu...

Alternative Titles

Full title

Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2769373574

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2769373574

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-022-01239-7

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