Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
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Author / Creator
Cheng, Yuan , He, Chen-Yang , Tian, Ding-Yuan , Chen, Si-Han , Ren, Jun-Rong , Sun, Hao-Lun , Xu, Man-Yu , Tan, Cheng-Rong , Fan, Dong-Yu , Jian, Jie-Ming , Sun, Pu-Yang , Zeng, Gui-Hua , Shen, Ying-Ying , Shi, An-Yu , Jin, Wang-Sheng , Bu, Xian-Le , Liu, Hong-Ming , Xu, Yu-Ming , Wang, Jun and Wang, Yan-Jiang
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Cerebral amyloid-β (Aβ) accumulation due to impaired Aβ clearance is a pivotal event in the pathogenesis of Alzheimer’s disease (AD). Considerable brain-derived Aβ is cleared via transporting to the periphery. The liver is the largest organ responsible for the clearance of metabolites in the periphery. Whether the liver physiologically clears circu...
Alternative Titles
Full title
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
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Record Identifier
TN_cdi_proquest_miscellaneous_2791374913
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2791374913
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-023-02559-z
