Regulating GSDMB pore formation: to ignite or inhibit?
Regulating GSDMB pore formation: to ignite or inhibit?
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In the recent Nature, Wang et al. and Zhong et al. present the cryo-EM structures of Gasdermin B (GSDMB) pore and strucures of GSDMB in complex with a
Shigella
effector, IpaH7.8. The structures shed light on the structural mechanisms that govern GSDMB-mediated pyroptosis, a process that is regulated by pathogenic bacteria and alternative spli...
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Full title
Regulating GSDMB pore formation: to ignite or inhibit?
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TN_cdi_proquest_miscellaneous_2800146585
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2800146585
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ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/s41418-023-01163-8
