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Ruan, Jianbin
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: QIU-SAQ, 2022, p.9773-9773
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Ruan, Jianbin
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: RA-SAU, 2021, p.9742-9742
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ArticlesPeer ReviewedFull Text
Cryo-EM structure of the gasdermin A3 membrane pore
Author / Creator:Ruan, Jianbin ; Xia, Shiyu ; Liu, Xing ; Lieberman, Judy ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-05, Vol.557 (7703), p.62-67
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Author / Creator:Hu, Jun Jacob ; Liu, Xing ; Xia, Shiyu ; Zhang, Zhibin ; Zhang, Ying ; Zhao, Jingxia ; Ruan, Jianbin ; Luo, Xuemei ; Lou, Xiwen ; Bai, Yang ; Wang, Junhong ; Hollingsworth, L. Robert ; Magupalli, Venkat Giri ; Zhao, Li ; Luo, Hongbo R. ; Kim, Justin ; Lieberman, Judy ; Wu, Hao
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-07, Vol.21 (7), p.736-745
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An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis
Author / Creator:Wang, Chengliang ; Ruan, Jianbin
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2023-05, Vol.21 (5), p.e3002103-e3002103
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Author / Creator:Liu, Xing ; Zhang, Zhibin ; Ruan, Jianbin ; Pan, Youdong ; Magupalli, Venkat Giri ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.153-158
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ArticlesPeer ReviewedFull Text
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
Author / Creator:Zanoni, Ivan ; Tan, Yunhao ; Di Gioia, Marco ; Broggi, Achille ; Ruan, Jianbin ; Shi, Jianjin ; Donado, Carlos A. ; Shao, Feng ; Wu, Hao ; Springstead, James R. ; Kagan, Jonathan C.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6290), p.1232-1236
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SERPINB1-mediated checkpoint of inflammatory caspase activation
Author / Creator:Choi, Youn Jung ; Kim, Stephanie ; Choi, Younho ; Nielsen, Travis B. ; Yan, Jun ; Lu, Alvin ; Ruan, Jianbin ; Lee, Hye-Ra ; Wu, Hao ; Spellberg, Brad ; Jung, Jae U.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-03, Vol.20 (3), p.276-287
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Molecular mechanism for NLRP6 inflammasome assembly and activation
Author / Creator:Shen, Chen ; Lu, Alvin ; Xie, Wen Jun ; Ruan, Jianbin ; Negro, Roberto ; Egelman, Edward H. ; Fu, Tian-Min ; Wu, Hao
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (6), p.2052-2057
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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes
Author / Creator:Robert Hollingsworth, L. ; David, Liron ; Li, Yang ; Griswold, Andrew R. ; Ruan, Jianbin ; Sharif, Humayun ; Fontana, Pietro ; Orth-He, Elizabeth L. ; Fu, Tian-Min ; Bachovchin, Daniel A. ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.189-189, Article 189
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Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
Author / Creator:Zhang, Liman ; Chen, Shuobing ; Ruan, Jianbin ; Wu, Jiayi ; Tong, Alexander B. ; Yin, Qian ; Li, Yang ; David, Liron ; Lu, Alvin ; Li Wang, Wei ; Marks, Carolyn ; Ouyang, Qi ; Zhang, Xinzheng ; Mao, Youdong ; Wu, Hao
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-10, Vol.350 (6259), p.404-409
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ArticlesPeer ReviewedFull Text
3D Artificial Array Interface Engineering Enabling Dendrite-Free Stable Zn Metal Anode
Author / Creator:Ruan, Jianbin ; Ma, Dingtao ; Ouyang, Kefeng ; Shen, Sicheng ; Yang, Ming ; Wang, Yanyi ; Zhao, Jinlai ; Mi, Hongwei ; Zhang, Peixin
Publisher:Singapore: Springer Nature Singapore
Journal title:Nano-micro letters, 2023-12, Vol.15 (1), p.37-37, Article 37
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Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin
Author / Creator:Russo, Ashley J. ; Vasudevan, Swathy O. ; Méndez-Huergo, Santiago P. ; Kumari, Puja ; Menoret, Antoine ; Duduskar, Shivalee ; Wang, Chengliang ; Pérez Sáez, Juan M. ; Fettis, Margaret M. ; Li, Chuan ; Liu, Renjie ; Wanchoo, Arun ; Chandiran, Karthik ; Ruan, Jianbin ; Vanaja, Sivapriya Kailasan ; Bauer, Michael ; Sponholz, Christoph ; Hudalla, Gregory A. ; Vella, Anthony T. ; Zhou, Beiyan ; Deshmukh, Sachin D. ; Rabinovich, Gabriel A. ; Rathinam, Vijay A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2021-02, Vol.22 (2), p.154-165
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ArticlesPeer ReviewedFull Text
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Author / Creator:Bian, Chuanbing ; Xu, Chao ; Ruan, Jianbin ; Lee, Kenneth K ; Burke, Tara L ; Tempel, Wolfram ; Barsyte, Dalia ; Li, Jing ; Wu, Minhao ; Zhou, Bo O ; Fleharty, Brian E ; Paulson, Ariel ; Allali-Hassani, Abdellah ; Zhou, Jin-Qiu ; Mer, Georges ; Grant, Patrick A ; Workman, Jerry L ; Zang, Jianye ; Min, Jinrong
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2011-07, Vol.30 (14), p.2829-2842
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ArticlesPeer ReviewedFull Text
NLRP inflammasomes in health and disease
Author / Creator:Xu, Zhihao ; Kombe Kombe, Arnaud John ; Deng, Shasha ; Zhang, Hongliang ; Wu, Songquan ; Ruan, Jianbin ; Zhou, Ying ; Jin, Tengchuan
Publisher:Singapore: Springer Nature Singapore
Journal title:Molecular biomedicine, 2024-04, Vol.5 (1), p.14-43, Article 14
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ArticlesPeer ReviewedFull Text
Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation
Author / Creator:Choi, Youn Jung ; Kim, Stephanie ; Choi, Younho ; Nielsen, Travis B. ; Yan, Jun ; Lu, Alvin ; Ruan, Jianbin ; Lee, Hye-Ra ; Wu, Hao ; Spellberg, Brad ; Jung, Jae U.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-05, Vol.20 (5), p.664-664
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Regulating GSDMB pore formation: to ignite or inhibit?
Author / Creator:Ruan, Jianbin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2023-06, Vol.30 (6), p.1401-1403
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ArticlesPeer ReviewedFull Text
Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9
Author / Creator:Li, Jing ; Li, Zhihong ; Ruan, Jianbin ; Xu, Chao ; Tong, Yufeng ; Pan, Patricia W. ; Tempel, Wolfram ; Crombet, Lissete ; Min, Jinrong ; Zang, Jianye
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-10, Vol.6 (10), p.e25104-e25104
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Structural Basis of the Chromodomain of Cbx3 Bound to Methylated Peptides from Histone H1 and G9a
Author / Creator:Ruan, Jianbin ; Ouyang, Hui ; Amaya, Maria F. ; Ravichandran, Mani ; Loppnau, Peter ; Min, Jinrong ; Zang, Jianye
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e35376-e35376
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Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1
Author / Creator:Li, Yang ; Fu, Tian-Min ; Lu, Alvin ; Witt, Kristen ; Ruan, Jianbin ; Shen, Chen ; Wu, Hao
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (43), p.10845-10852
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Ruan, Jianbin

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Ruan, Jianbin

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Cryo-EM structure of the gasdermin A3 membrane pore

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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

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An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

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SERPINB1-mediated checkpoint of inflammatory caspase activation

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Molecular mechanism for NLRP6 inflammasome assembly and activation

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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes

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Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

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3D Artificial Array Interface Engineering Enabling Dendrite-Free Stable Zn Metal Anode

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Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

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Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

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NLRP inflammasomes in health and disease

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Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation

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Regulating GSDMB pore formation: to ignite or inhibit?

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Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9

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Structural Basis of the Chromodomain of Cbx3 Bound to Methylated Peptides from Histone H1 and G9a

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Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1

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