Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril...
Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure
About this item
Full title
Author / Creator
Luo, Hong-Yu , Gao, Li-Chen , Long, Hui-Zhi , Zhou, Zi-Wei , Xu, Shuo-Guo , Li, Feng-Jiao , Li, Hong-Li , Cheng, Yan , Li, Cai-Xia , Peng, Xing-Yu , Li, Liang , Chen, Ran and Deng, Ping
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Objective
Sacubitril/valsartan is a commonly used medicine for treating heart failure (HF) patients, but the treatment effects significantly vary. Neprilysin (NEP) and carboxylesterase 1 (CES1) play an important role in the efficacy of sacubitril/valsartan. The purpose of this study was to explore the relationship between
NEP
and
CES1
Alternative Titles
Full title
Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2802423317
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2802423317
Other Identifiers
ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-023-03484-6
