Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the ki...
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-dependent, lipid peroxidation-driven membrane destruction that can be inhibited by glutathione peroxidase 4. Morphologically, it is characterized by cellular, organelle and cytoplasmic swelling and the loss of plasma membrane integrity, with the release of intracellul...
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Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney
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TN_cdi_proquest_miscellaneous_2805026483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2805026483
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ISSN
1759-5061
E-ISSN
1759-507X
DOI
10.1038/s41581-023-00689-x