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Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the ki...

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the ki...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2805026483

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney

About this item

Full title

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Nephrology, 2023-05, Vol.19 (5), p.315-336

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-dependent, lipid peroxidation-driven membrane destruction that can be inhibited by glutathione peroxidase 4. Morphologically, it is characterized by cellular, organelle and cytoplasmic swelling and the loss of plasma membrane integrity, with the release of intracellul...

Alternative Titles

Full title

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2805026483

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2805026483

Other Identifiers

ISSN

1759-5061

E-ISSN

1759-507X

DOI

10.1038/s41581-023-00689-x

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