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Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic margi...

Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic margi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2807915669

Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic marginal zone lymphoma

About this item

Full title

Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic marginal zone lymphoma

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2023-07, Vol.37 (7), p.1485-1498

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The role of the tumor microenvironment (TME) and intratumoral T cells in splenic marginal zone lymphoma (sMZL) is largely unknown. In the present study, we evaluated 36 sMZL spleen specimens by single cell analysis to gain a better understanding of the TME in sMZL. Using mass cytometry (CyTOF), we observed that the TME in sMZL is distinct from that...

Alternative Titles

Full title

Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic marginal zone lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2807915669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2807915669

Other Identifiers

ISSN

0887-6924,1476-5551

E-ISSN

1476-5551

DOI

10.1038/s41375-023-01911-2

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