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CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of...

CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2807916239

CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels

About this item

Full title

CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels

Publisher

United States: Nature Publishing Group

Journal title

Nature aging, 2022-11, Vol.2 (11), p.1040-1053

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

Development of disease-modifying therapies against Alzheimer's disease (AD) requires biomarkers reflecting the diverse pathological pathways specific for AD. We measured 665 proteins in 797 cerebrospinal fluid (CSF) samples from patients with mild cognitive impairment with abnormal amyloid (MCI(Aβ+): n = 50), AD-dementia (n = 230), non-AD dementias...

Alternative Titles

Full title

CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2807916239

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2807916239

Other Identifiers

ISSN

2662-8465

E-ISSN

2662-8465

DOI

10.1038/s43587-022-00300-1

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