Non-specificity as the sticky problem in therapeutic antibody development
Non-specificity as the sticky problem in therapeutic antibody development
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Antibodies are highly potent therapeutic scaffolds with more than a hundred different products approved on the market. Successful development of antibody-based drugs requires a trade-off between high target specificity and target binding affinity. In order to better understand this problem, we here review non-specific interactions and explore their...
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Full title
Non-specificity as the sticky problem in therapeutic antibody development
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TN_cdi_proquest_miscellaneous_2807916504
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2807916504
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ISSN
2397-3358
E-ISSN
2397-3358
DOI
10.1038/s41570-022-00438-x
